Evaluation of binding properties of Plantago psyllium seed mucilage.

نویسندگان

  • Majid Saeedi
  • Katayoun Morteza-Semnani
  • Farshad Ansoroudi
  • Saeed Fallah
  • Gholamreza Amin
چکیده

Mucilage extracted from Plantago psyllium seeds was evaluated for inertness and safety parameters. The suitability of psyllium mucilage for a pharmaceutical binder was assessed in paracetamol tablets. Properties of the granules prepared using different concentrations of psyllium mucilage was compared with PVP and tragacanth. Psyllium mucilage at 5 % (m/m) was found to be comparable with 3 % (m/m) of PVP. Investigated paracetamol tablets indicated that psyllium mucilage can retard the drug release.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Evaluation of Buccoadhesive Propranolol Hydrochloride Formulations Containing Plantago psyllium Seed Mucilage and Carbopol 934P

Drug delivery via buccal mucosa by means of buccoadhesive formulations offer distinct advantages over peroral administration. Recently, plant gums and exudates have been screened for their use as pharmaceutical adjuvants. The aim of this study is to evaluate matrix tablets containing Plantago psyllium seed mucilage in addition to carbopol as a mucoadhesive agent, and propranolol hydrochloride a...

متن کامل

Effects of Foliar Application of Fe and Zn on Seed Yield and Mucilage Content of Psyllium (Plantago psyllium) at Different Stages of Maturity

In order to evaluate the effects of foliar application of micronutrients (iron and zinc) and different harvesting times during seed filling on yield and mucilage percentage of psyllium (Plantago psyllium), a field experiment was carried out in 2009 at the Research Farm of the Faculty of Agriculture, University of Tabriz, Tabriz, Iran. The experiment was arranged as split plot based on randomize...

متن کامل

تأثیر تنش خشکی و تراکم بر صفات کمی و کیفی دوگونه دارویی اسفرزه اواتا (Plantago ovata Forssk) و اسفرزه پسیلیوم (Plantago psyllium L.)

In order to investigate yield, yield components and quality traits of P. ovata and P. psyllium under water stress and plant density, two experiments were conducted at the Agriculture Research Field, University of Tehran, Karaj, in April 2005 and 2006. Two Factorial experiments based on randomized complete block design with three replications were used. The treatments were three levels of water ...

متن کامل

The effect of Plantago major seed mucilage combined with carbopol on the release profile and bioadhesive properties of propranolol HCl buccoadhesive tablets

Buccoadhesive drug delivery systems have distinct advantages in comparison with oral administration. Plant exudates like gum or mucilage are being studied for their use as pharmaceutical adjuvant. The aim of this study is to evaluate the properties of the Plantago major seed mucilage as a mucoadhesive agent and propranolol hydrochloride is chosen as a model drug. Mucoadhesive tablets of propran...

متن کامل

“Sticky invasion” – the physical properties of Plantago lanceolata L. seed mucilage

The mucilage envelope of seeds has various functions including the provision of different ways for the dispersal of diaspores. Chemical composition and water content of the mucilage yield particular adhesive and frictional properties in the envelope that also influence the dispersal of seeds. To determine the physical properties of Plantago lanceolata seed mucilage we studied (1) composition, (...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Acta pharmaceutica

دوره 60 3  شماره 

صفحات  -

تاریخ انتشار 2010